In line with this, FISH analysis showed that condition LaD did not contain more chromosomally abnormal cells than LaA (p = 0.60; Student’s t test), and although the basal level of abnormal cells in laminin-521 cultures appeared higher than on feeder layers, this difference did not reach statistical significance (p = 0.11, Student’s t test; Figure 5 I and Table S3 ).
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Higher-Density Culture in Human Embryonic Stem Cells Results in DNA Damage and Genome Instability.
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