Hypoxia-induced nitric oxide production and tumour perfusion is inhibited by pegylated arginine deiminase (ADI-PEG20).

Sci Rep · 2016 · PMC4789736 · PMID 26972697

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did not reach statistical significanceno p-value reported

In these tumours, the increase in hypoxic fraction did not reach statistical significance ( Fig. 8F ).

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