Germline polymorphisms in genes involved in the Hippo pathway as recurrence biomarkers in stages II/III colon cancer.

Pharmacogenomics J · 2016 · PMC4792794 · PMID 26370619

Europe PMC DOI

hedged sentence

0.0770

closest p · 1.5× alpha

0.0770

boldest claim

The sentences

did not reach statistical significancep =0.077so close (0.05 < p ≤ 0.1)

Patients with a CT or TT genotype had a 28% (±5% SE) 3-year recurrence probability compared to 40% (±5% SE) for patients with a homozygous wild type CC genotype, although this association did not reach statistical significance (HR: 0.66; 95% CI, 0.41–1.05; p =0.077).

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