Evaluation of a Mixing versus a Cycling Strategy of Antibiotic Use in Critically-Ill Medical Patients: Impact on Acquisition of Resistant Microorganisms and Clinical Outcomes.

37.5/100 patient-days), the difference did not reach statistical significance (p = 0.1).

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However, the difference in shock was barely significant and the magnitude of the differences in the severity scores, though statistically significant, was of doubtful clinical meaning.

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