Effects of Sex and Mild Intrainsult Hypothermia on Neuropathology and Neural Reorganization following Neonatal Hypoxic Ischemic Brain Injury in Rats.

Neural Plast · 2016 · PMC4794561 · PMID 27042359

Europe PMC DOI

hedged sentences

0.0560

closest p · 1.1× alpha

0.0600

boldest claim

The sentences

near-significantp = 0.056so close (0.05 < p ≤ 0.1)

We then performed a 4 (Area) × 2 (Sex) × 3 (Treatment; sham, HI normothermic, and HI hypothermic) repeated measures ANOVA using just the measurements from the contralateral hemisphere and found a significant effect of Area [ F (3,156) = 343.947, p < 0.05], a near-significant Sex effect [ F (1,52) = 3.807, p = 0.056], and trend for a significant Treatment × Sex interaction [ F (2,52) = 2.473, p = 0.09] (see Table 3 for averages and standard errors for each subregion for all groups).

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marginally significantp = 0.06so close (0.05 < p ≤ 0.1)

To assess HI effects independent of temperature modulation, a 4 (Area) × 2 (Sex) × 2 (Treatment; HI normothermic and sham) repeated measures ANOVA revealed a significant Sex × Treatment interaction [ F (1,37) = 5.621, p < 0.05], as well as a marginally significant Sex effect [ F (1,37) = 3.748, p = 0.06] and Area × Sex interaction [ F (1,37) = 2.996, p = 0.09].

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