Irradiation of necrotic cancer cells, employed for pulsing dendritic cells (DCs), potentiates DC vaccine-induced antitumor immunity against high-grade glioma.

Intriguingly, the amount of protein carbonylation in the different lysate preparations showed a highly significant linear correlation with the percentage of long-term surviving mice (R 2 = 0.96, p = 0.0028, Fig. 5C ).

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Although there was a decreased infiltration of these myeloid cell populations in FT-DC vaccine treated mice as compared to untreated mice, this did not reach statistical significance.

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