Glutathione S Transferases Polymorphisms Are Independent Prognostic Factors in Lupus Nephritis Treated with Cyclophosphamide.

PLoS One · 2016 · PMC4803192 · PMID 27002825

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closest p · 1.2× alpha

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The sentences

showed a trendp = 0.059so close (0.05 < p ≤ 0.1)

In univariate analysis, the polymorphism of GST, CYP2B6 and CYP2C19 did not influence the efficacy of CYC, except the Ile→105Val GSTP1 genotype, which showed a trend toward a lower probability of achieving GR (72.4% versus 91.2%, p = 0.059).

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