SMS2 deficiency showed a trend for decreased C18–C24-SMs in the kidneys of mice fed with a HFD, but increased C22–C24-Cers ( Fig 3A and 3B ).
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Imaging Mass Spectrometry Reveals Acyl-Chain- and Region-Specific Sphingolipid Metabolism in the Kidneys of Sphingomyelin Synthase 2-Deficient Mice.
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