Compared to WT, Brinp1 −/− mice showed a trend towards reduced number of calls, a longer latency to call and longer latency to investigate the cotton bud, but these parameters did not reach the 95 % confidence level (Fig. 4d, e ).
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Brinp1(-/-) mice exhibit autism-like behaviour, altered memory, hyperactivity and increased parvalbumin-positive cortical interneuron density.
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