not improve shock reversal or other clinical outcomes For the overall population of patients with shock post-cardiac arrest, corticosteroids did attenuate inflammation as represented by interleukin-6 levels For the subpopulation of patients with baseline adrenal insufficiency, corticosteroids had a near-significant improvement in shock reversal compared to placebo, though future studies with larger number of patients will be needed to evaluate this population.
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Corticosteroid therapy in refractory shock following cardiac arrest: a randomized, double-blind, placebo-controlled, trial.
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