Of interest, both CXCL4 and CXCL7 mRNA levels were found to be significantly elevated in patients with early RA compared with uninflamed controls, and showed a trend towards higher expression in early RA compared with patients with resolving arthritis.
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Expression of chemokines CXCL4 and CXCL7 by synovial macrophages defines an early stage of rheumatoid arthritis.
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