a significant trendP < 0.0001
The CURES Eye Study demonstrated a significant increase in the prevalence of DR with increasing glycated hemoglobin (HbA1c) levels.[ 3 ] The multiple logistic regression analysis carried out using DR as a dependent variable showed a significant trend of increasing retinopathy at different quartiles of HbA1c (trend χ 2 = 51.6, P < 0.0001) as shown in Fig. 1 .