CD8(+) T-cell pathogenicity in Rasmussen encephalitis elucidated by large-scale T-cell receptor sequencing.

RE patients' peripheral blood CD8 + TCR repertoire entropy was lower as compared with the non-CNS disease control groups headache ( P =0.007) and common cold ( P =0.020), while the differences to the childhood epilepsy control groups, TLE and CD did not reach statistical significance ( Fig. 1g , unpaired t -test with Welch's correction).

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