Cigarette Smoke Decreases the Maturation of Lung Myeloid Dendritic Cells.

Although highly significant positive correlations between mDCs subtypes were present in all groups, a positive association between myeloid and plasmacytoid subtypes was observed for COPD patients only.

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There was a trend toward a higher number of follicular DCs (CD21 + ) in the peribronchial lymphoid tissue of COPD patients compared with non-COPD subjects (22.2% versus 15.8%, respectively), although the difference failed to reach statistical significance ( Fig 3A ).

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