DNA demethylation caused by 5-Aza-2'-deoxycytidine induces mitotic alterations and aneuploidy.

Oncotarget · 2016 · PMC4826165 · PMID 26771138

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a clear trendno p-value reported

Specifically, after 24 hours of treatment we observed a 30% reduction in the number of cells with 45 chromosomes and concurrently a significant increase in aneuploid cells with a clear trend to hypodiploidy.

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