Cell-free circulating mitochondrial DNA content and risk of hepatocellular carcinoma in patients with chronic HBV infection.

Sci Rep · 2016 · PMC4827061 · PMID 27063412

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borderline significantno p-value reported

However, none of these variables exhibited a significant interaction with mtDNA content, except gender for which a borderline significant interaction was noted ( P for interaction = 0.087) ( Table 4 ).

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a significant trendno p-value reported

Interestingly, a significant trend of reduction in mtDNA content was noticed in HBV patients who developed into HCC during follow up, consistent with the results of the main effects analysis of our study.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.