a strong trendP =0.065
There were no significant changes in serum concentrations of total cholesterol, triglycerides, LDL or HDL among patients following BROM-QR treatment ( Table 2 ). Interestingly, serum creatinine concentration had a strong trend toward decreasing (-0.04±0.02 mg/dL; P =0.065) as the estimated glomerular filtration rate significantly increased (+3.8±1.7 mL/min; P =0.026) following BROM-QR therapy.