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A randomized, blinded study to evaluate the efficacy and safety of umeclidinium 62.5 μg compared with tiotropium 18 μg in patients with COPD.

Int J Chron Obstruct Pulmon Dis · 2016 · PMC4827908 · PMID 27103795

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Interestingly, the treatment difference for trough FEV 1 and FVC did not reach statistical significance after the first dose (day 2) but was apparent at day 28, the first assessment after repeat dosing.

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