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Factors associated with sinus bradycardia during crizotinib treatment: a retrospective analysis of two large-scale multinational trials (PROFILE 1005 and 1007).

Cancer Med · 2016 · PMC4831279 · PMID 26823131

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This suggests that the concomitant use of beta‐blockers increases the risk of developing SB during crizotinib treatment, although this association did not reach statistical significance in the multivariable logistic regression analysis.

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