A Bayesian Approach to the Overlap Analysis of Epidemiologically Linked Traits.

Genes that have previously been identified as containing SNPs that are genome‐wide significantly associated with obesity‐related phenotypes (Ensembl; http://www.ensembl.org/index.html ) are labeled with a double asterisk in Table 3 , whereas those that have been observed as highly significant ( P ‐value < 9 × 10 –5 ) have a single asterisk.

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When π 0 = 0.99, there is a clear trend of more significant P ‐values for the ABF analysis route, whereas the frequentist route counts are not considered to be different from chance at significance level 0.05 at R = 1 for both P ‐value thresholds, as well as at R = 2 and 4 for the lower α threshold.

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