Genetic Variants in the Bone Morphogenic Protein Gene Family Modify the Association between Residential Exposure to Traffic and Peripheral Arterial Disease.

PLoS One · 2016 · PMC4833382 · PMID 27082954

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nominally significantP < 0.05actually significant

Further investigation of BMP8A using the Genotype Tissue Expression Database revealed multiple variants with nominally significant (P < 0.05) interaction P-values in our EA cohort were significant BMP8A eQTLs in tissue types highlight relevant for PAD such as rs755249 (tibial nerve, eQTL P = 3.6x10 -6 ) and rs1180341 (tibial artery, eQTL P = 5.3x10 -6 ).

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