A Combination of CD28 (rs1980422) and IRF5 (rs10488631) Polymorphisms Is Associated with Seropositivity in Rheumatoid Arthritis: A Case Control Study.

PLoS One · 2016 · PMC4836711 · PMID 27092776

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did not reach statistical significanceno p-value reported

This, together with the fact that the association analysis in this study was done on the whole group of patients regardless the antibody status, with 34.5% of ACPA negative patients from 499 cases analysed, might rationalize why these genes did not reach statistical significance.

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