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The Effectiveness of Percutaneous Vertebroplasty Is Determined by the Patient-Specific Bone Condition and the Treatment Strategy.

PLoS One · 2016 · PMC4839558 · PMID 27100630

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a clear trendno p-value reported
For all cement volumes, we found treatment strategies that affected fracture risk both positively and negatively; however, with a clear trend towards higher cement volumes resulting in lower predicted fracture risk.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.