Prolonged Drainage and Intrapericardial Bleomycin Administration for Cardiac Tamponade Secondary to Cancer-Related Pericardial Effusion.

The authors reported an increased rate of effusion failure-free survival at 2 months, although the difference did not reach statistical significance. 28 Moreover, in a head-to-head comparison with Doxycycline, Bleomycin has been shown to have fewer side effects and to lead to shorter hospitalizations. 29 Thus, when talcage is performed, Bleomycin can be considered an active and safe agent.

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