Barely Significant
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Role of Titin Missense Variants in Dilated Cardiomyopathy.

J Am Heart Assoc · 2015 · PMC4845231 · PMID 26567375

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We also noted that “likely” and “possibly” carriers of TTN variants with double or compound heterozygous mutations (Table 1 ) had lower left ventricular ejection fractions (29±16%) compared with those with single missense variants (34±14%), although because of the small number of observations the difference did not reach statistical significance.

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