However, these were not adequately powered and failed to reach statistical significance (P interaction =0.2 for prasugrel and P interaction =0.13 for ticagrelor). 27 29 Reassuringly, there was no increased risk of major bleeding risk in any group, independent of antiplatelet or DM management strategy ( figure 4 ).
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Systematic review and meta-analysis of optimal P2Y12 blockade in dual antiplatelet therapy for patients with diabetes with acute coronary syndrome.
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