However, separation into discrete subpopulations, AMF7-63 + B8H10 − , AMF7-63 + B8H10 + , or B8H10 + AMF7-63 − mitochondria yielded no significant differences between the groups in terms of mitochondrial size/volume, although AMF7-63 + and AMF7-63 + B8H10 + showed a trend toward increased volume (data not shown).
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ALS-linked misfolded SOD1 species have divergent impacts on mitochondria.
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