highly significantP = 0.02
Pathway analysis revealed the cell adhesion molecules pathway as the most highly significant pathway associated with drusen progression (corrected P = 0.02).
Pathway analysis revealed the cell adhesion molecules pathway as the most highly significant pathway associated with drusen progression (corrected P = 0.02).
In single marker tests of the SNPs that make up the risk score, we found a nominally significant association with rs943080 in VEGFA within the AREDS dataset ( P = 0.028; Table 2 ); this does not replicate in the CWRU/HIHG dataset.