Effect of folate status and methylenetetrahydrofolate reductase genotypes on the complications and outcome of high dose methotrexate chemotherapy in north Indian children with acute lymphoblastic leukemia.

Indian J Med Paediatr Oncol · 2016 · PMC4854052 · PMID 27168705

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did not reach statistical significanceno p-value reported

Though, the mean pretherapy folate levels were higher in MTHFR 677 wild (CC) genotype (7.89 ± 6.23 ng/ml) as compared to that in mutant (CT+TT) genotypes (6.06 ± 5.61 ng/ml), the difference did not reach statistical significance.

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