Neither treatment modified triglyceride or HDL-c serum levels, although there was a slight trend towards increased HDL-c levels in response to GQ-16 treatment ( Table 1 ).
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GQ-16, a TZD-Derived Partial PPARγ Agonist, Induces the Expression of Thermogenesis-Related Genes in Brown Fat and Visceral White Fat and Decreases Visceral Adiposity in Obese and Hyperglycemic Mice.
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On the other hand, this BAT depot was darker and showed a trend towards decreased (by 49.7%) mass in response to GQ-16 treatment ( Fig 4A and 4B ).