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Dobutamine stress echocardiography for assessment of systolic function in dogs with experimentally induced mitral regurgitation.

J Vet Intern Med · 2014 · PMC4858017 · PMID 24433339

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5 The decrease in torsional deformations at baseline (without dobutamine infusion), which agree with previous studies, 5 , 26 , 27 may reflect deterioration in myocardial contractility with disease progression, although these changes did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.