Deregulated hedgehog pathway signaling is inhibited by the smoothened antagonist LDE225 (Sonidegib) in chronic phase chronic myeloid leukaemia.

Sci Rep · 2016 · PMC4860619 · PMID 27157927

Europe PMC DOI

hedged sentence

0.1000

closest p · 2.0× alpha

0.1000

boldest claim

The sentences

did not reach statistical significancep = 0.1so close (0.05 < p ≤ 0.1)

There was a trend for up-regulation of GLI1 in CP-CML LSC, but this did not reach statistical significance (p = 0.1).

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