Barely Significant
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Small Changes, But Huge Impact? The Right Anterior Insula's Loss of Connection Strength during the Transition of Old to Very Old Age.

Front Aging Neurosci · 2016 · PMC4861722 · PMID 27242508

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showed a trendno p-value reported
The same reverse relationship between increasing age and connection strength could be observed for the ICC cluster in the left SFG: Originally, positively connected networks/ROIs now showed a trend to become anti-correlated with increasing age and vice versa, originally anti-correlated networks/ROI's exhibited a trend to become positively correlated.

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