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Mechanical Circulatory Support in Children.

Curr Cardiol Rev · 2016 · PMC4861942 · PMID 27048145

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a clear trendno p-value reported
In fact in the adult population there has been a clear trend toward earlier institution of VAD support, prior to the patient incurring end organ injury.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.