Barely Significant
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Enhanced replication of avian-origin H3N2 canine influenza virus in eggs, cell cultures and mice by a two-amino acid insertion in neuraminidase stalk.

Vet Res · 2016 · PMC4862097 · PMID 27160077

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a decreasing trendno p-value reported
At 8 dpi, the r-06 infected group still kept a higher level of IFN-γ while r-06/NA2 infected group had a decreasing trend, and IFN-γ levels in the r-06 group were significantly higher than those in the r-06/NA2 group ( P = 0.023).

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However, the difference in the pathological scores of the lungs did not reach statistical significance between the two infected groups.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.