Differences in the Selection Bottleneck between Modes of Sexual Transmission Influence the Genetic Composition of the HIV-1 Founder Virus.

PLoS Pathog · 2016 · PMC4862634 · PMID 27163788

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did not reach statistical significanceno p-value reported

Detailed analyses of the variable loops revealed only one such putative association with MSM founder viruses encoding a more compact V2 loop compared to HSX founder viruses (mean of 40.9 residues for MSM and 42.5 for HSX) although such an effect did not reach statistical significance after correcting for multiple comparisons.

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