These effects did not reach statistical significance (Figures 1(e) and 1(f) , p = 0.39 to 0.96), with the exception of the cone b-wave, which was significantly reduced following IV injection of isoguvacine ( Figure 1(g) , −51 ± 11%, p < 0.05).
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Retinal Electrophysiology Is a Viable Preclinical Biomarker for Drug Penetrance into the Central Nervous System.
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