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An activation-induced IL-15 isoform is a natural antagonist for IL-15 function.

Sci Rep · 2016 · PMC4863161 · PMID 27166125

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It slightly inhibited the binding of IL-15 to IL-15Rα, but the difference did not reach statistical significance (The IL-15 group compared with the IL-15 plus IL-15ΔE6 inhibition group).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.