Acute blockade of IL-25 in a colitis associated colon cancer model leads to increased tumor burden.

Sci Rep · 2016 · PMC4863374 · PMID 27165713

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marginally significantno p-value reported

Mice treated with the α-IL-25 antibody had similar expression levels in all these genes, with a marginally significant decrease in Vegfa compared to isotype treated mice ( Fig. 4 ).

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showed a trendno p-value reported

Our evaluation of mRNA expression in the colons of mice treated with α-IL-25 showed a trend toward increased inflammatory cytokines in the Th17 pathway ( il-17a, il-22, and il-23p19 ).

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