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Drug reformulations and repositioning in the pharmaceutical industry and their impact on market access: regulatory implications.

J Mark Access Health Policy · 2014 · PMC4865781 · PMID 27226839

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a clear trendno p-value reported
In Europe, there is also a clear trend for reformulation cases being developed by the same company (77.1% of cases), with most of those cases being submitted through national procedure in all of the countries.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.