Comparative Effectiveness of Biosimilar, Reference Product and Other Erythropoiesis-Stimulating Agents (ESAs) Still Covered by Patent in Chronic Kidney Disease and Cancer Patients: An Italian Population-Based Study.

PLoS One · 2016 · PMC4871488 · PMID 27187174

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did not reach statistical significanceno p-value reported

Regarding age distribution, ESA users with CKD starting a treatment with a biosimilar appear to be older (mean age ± SD: 80.4±8.7) than those starting with the reference product (mean age ± SD: 64.5±14.7, p-value = 0.055) or ESAs covered by patent (mean age ± SD: 66.0 ±16.1, p-value = 0.057), despite they did not reach statistical significance.

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