Association of primary open-angle glaucoma with mitochondrial variants and haplogroups common in African Americans.

The m.16390G>A variant was also found to be more common in type 2 diabetes cases than in controls in a Tunisian study population, but the nominally significant association (p=0.04) did not survive multivariate regression analysis [ 47 ].

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The top seven associations have imputed p values of less than 1×10 −6 , and they would be highly significant if the population frequencies inferred from the pooled sequencing are correct.

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