A meta-analysis comparing cisplatin-based to carboplatin-based chemotherapy in moderate to advanced squamous cell carcinoma of head and neck (SCCHN).

Oncotarget · 2016 · PMC4872772 · PMID 26755647

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did not reach statistical significanceno p-value reported

After rejecting these two studies, the carboplatin group was also associated with a lower rate of grade≥3 nausea and vomiting, with an RR of 2.34 (95% CI, 0.62 to 8.91; P =0.21), but the difference did not reach statistical significance.

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