Developing a Gene Biomarker at the Tipping Point of Adaptive and Adverse Responses in Human Bronchial Epithelial Cells.

Furthermore, 11 additional targeted transcripts exhibited consistent differences compared with the microarray analysis but did not reach statistical significance resulting in a general concordance for 76% (22/29) of probed transcripts.

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The most highly significant biosets, -log( p -values), ranging from 6.4 to 14.37 originated from cigarette and tobacco smoke exposures with 51–68 genes positively correlated with our biomarker set.

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