Mitochondrial dysfunction and oxidative stress in patients with chronic kidney disease.

There was no effect of race on mitochondrial volume density and the difference in mitochondrial volume density between patients with CKD and controls remained highly significant after adjusting for race and age (Fig. 2 , P = 0.002).

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We also noted a trend toward an inverse association between lactate and mitochondrial DNA copy number but did not reach statistical significance.

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