Androgen-Sensitized Apoptosis of HPr-1AR Human Prostate Epithelial Cells.

PLoS One · 2016 · PMC4874596 · PMID 27203692

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The JC-1 staining profile showed a significant trend whereby DHT and STS synergistically increase mitochondrial membrane permeability ( Fig 4 ), suggesting that DHT renders mitochondria more vulnerable to intrinsic apoptotic stimuli and MOMP.

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