A subgroup analysis according to age (75–85 years [n=148] and >85 years [n=38]) showed a trend toward greater improvements in pain control and bowel function in the subgroup aged >85 years ( Figure 4 ).
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Switching to low-dose oral prolonged-release oxycodone/naloxone from WHO-Step I drugs in elderly patients with chronic pain at high risk of early opioid discontinuation.
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