The ΔF508 Mutation in the Cystic Fibrosis Transmembrane Conductance Regulator Is Associated With Progressive Insulin Resistance and Decreased Functional β-Cell Mass in Mice.

Intraperitoneal insulin tolerance test performed at 12 weeks of age showed a trend toward increased insulin sensitivity in male ( Fig. 3 G ), but not female ( Fig. 3 H ), ΔF508 homo- and heterozygous mutant mice.

also in 53,322 other papers

There was a nonsignificant trend in ΔF508 males ( Fig. 1 C ) but not females ( Fig. 1 D ) to gain less weight than controls.

also in 5,406 other papers