Effective Small Interfering RNA Therapy to Treat CLCN7-dependent Autosomal Dominant Osteopetrosis Type 2.

Treated mice also showed a trend of reduction of ParaThyroid Hormone (PTH) ( Figure 3f ), decrease of osteoclast number over bone perimeter and osteoclast surface over bone surface ( Figure 3g – i ), and reduction of mRNA expression of osteoclast-specific genes ( Figure 3j ), which are in agreement with the reduced serum levels of TRAcP ( Figure 2d ).

also in 53,322 other papers