Developmentally Sensitive Interaction Effects of Genes and the Social Environment on Total and Subcortical Brain Volumes.

Because longitudinal developmental studies have found curvilinear developmental trajectories with age for cortical and subcortical GM volumes, with the steepest growth found in early childhood and reductions reported from (pre)adolescence onwards [ 39 – 41 ], we tested 2- and 3-way interactions with age and age 2 (i.e., Age/Age 2 xG, Age/Age 2 xE, and Age/Age 2 xGxE) which were dropped from the model when not significant or nominally significant (i.e., did not survive correction for multiple testing).

also in 7,732 other papers